Medusa has been working as a Communications Tech but she would jump at the chance to be involved in navigation. The Moira's tech is well behind what the Inhumans and the Kree are used to, and she's fully capable of piloting ships (and has done so on occasion, although normally she has people for that.) In addition she's spent twenty years as queen of a people who keep migrating back and forth from space, so she's known astronomy and interstellar navigation for some time, and been involved in making the decisions on where to go, how to get there and how to negotiate diplomatically when they get there (or, alternatively, how to make war and win.) And she knows how to be in charge and lead on both a large scale with a kingdom/empire and small scale with a team of people. She likes being in charge and she's fully prepared to always assume responsibility.